KNOWLEDGE GRAPH-FIRST BIOMEDICAL INTELLIGENCE

We do the evidence work.
Scientists make the decisions.

Vexiom turns fragmented biomedical evidence into decision-ready target packages. A knowledge graph-first biomedical intelligence for target evaluation, evidence synthesis and decision-ready research packages.

01ComprehensiveRelevant evidence assembled across the sources that matter
02ContextualisedFindings interpreted in the biological setting in which they were observed
03TraceableImportant assertions linked back to their supporting evidence

The evidence work Vexiom performs

Scientists spend too much time assembling evidence instead of deciding what it means.

Modern biology produces more plausible targets than expert teams can evaluate with confidence. The hard part is no longer finding another hypothesis. It is building a rigorous, reproducible view of the evidence around each one.

1

Search

Find the relevant literature, structured data, genetics and perturbation evidence.

2

Reconcile

Resolve aliases, identifiers, duplicated claims and inconsistent annotations.

3

Contextualise

Compare findings across tissue, cell type, disease, model, assay and species.

4

Evaluate

Assess causal strength, contradictions, uncertainty, safety and decision relevance.

5

Package

Turn the analysis into a clear scientific case that can be reviewed and acted on.

THE VEXIOM DIFFERENCE

A connected evidence graph, not another search tool.

Our knowledge graph-first approach connects fragmented evidence while preserving biological context, provenance and uncertainty. The result is a scientific assessment that can be reviewed, challenged and used to guide the next decision.

The product

A decision-ready target package.

A polished, structured and updateable research package that makes both the scientific case and the uncertainty explicit.

Vexiom deliverableTarget
package
01

Human evidence

Genetics, patient expression and disease relevance

02

Mechanism

Pathways, interactions and biological rationale

03

Perturbation evidence

What happened when the biology was changed

04

Traceability

Citations, identifiers, provenance and supporting data

05

Risk & contradiction

Safety signals, null results and conflicting findings

06

Next experiments

The studies most likely to resolve remaining uncertainty

What makes the evaluation useful

Not more information.
A clearer basis for a decision.

The evidence has value only when it is interpreted rather than merely collected.

01

Biological context

Findings are interpreted in the tissue, cell type, disease, experimental system, perturbation and species in which they were observed.

02

Causal strength

Associative findings are kept distinct from functional, perturbational and human genetic evidence.

03

Contradiction and uncertainty

Null results, conflicting findings and unanswered questions are surfaced rather than averaged away.

04

End-to-end traceability

Important claims carry provenance, confidence and the underlying evidence needed for scientific review.

How an engagement works

Engagements begin with a target, shortlist or scientific question.
Vexiom builds the evidence package.

TAILORED ENGAGEMENTS

In tailored engagements, Vexiom can incorporate proprietary datasets and internal experimental evidence.

Target prioritisationCompare candidates on a consistent evidence basis
Portfolio reviewReassess the scientific case as evidence evolves
Early due diligencePressure-test the evidence around an external opportunity
Experiment planningIdentify the studies that would be most decision-changing

Get in touch

Better target decisions start with better evidence.
Vexiom builds the evidence around them.

Vexiom welcomes conversations with pharmaceutical R&D teams, scientific collaborators and investors.